The secretome profiling of a pediatric airway epithelium infected with human respiratory syncytial virus (hRSV) identified aberrant apical/basolateral trafficking and novel immune modulating (CXCL6, CXCL16, CSF3) and antiviral (CEACAM1) proteins
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چکیده
منابع مشابه
Induction and Antagonism of Antiviral Responses in Respiratory Syncytial Virus-Infected Pediatric Airway Epithelium.
UNLABELLED Airway epithelium is the primary target of many respiratory viruses. However, virus induction and antagonism of host responses by human airway epithelium remains poorly understood. To address this, we developed a model of respiratory syncytial virus (RSV) infection based on well-differentiated pediatric primary bronchial epithelial cell cultures (WD-PBECs) that mimics hallmarks of RS...
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15 صفحه اولRespiratory syncytial virus and human bronchial epithelium.
BACKGROUND A suitable model for respiratory syncytial virus (RSV) infection has yet to be developed. OBJECTIVE To describe an in vitro model of human respiratory epithelium in primary cell culture linked with a computer microscope interface that allows evaluation and imaging of living RSV-infected respiratory epithelium. DESIGN A descriptive, controlled study. Human bronchial cells were obt...
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ژورنال
عنوان ژورنال: Access Microbiology
سال: 2019
ISSN: 2516-8290
DOI: 10.1099/acmi.ac2019.po0458